Public Dissemination Event

El Puerto de Santa María, 3rd October 2019

Development of immune competence in sole (Solea senegalensis) and microalgae as a modulatory factor



Ana Patricia Mateus1,2; Carlos Carballo3,4; Lalia Mantecón5; Patricia IS Pinto1; Babak Najafpour1; Manuel Manchado3,6; Deborah M. Power1


1Centre of Marine Sciences (CCMAR), Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

2Escola Superior de Saúde da Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

3IFAPA Centro El Toruño, Junta de Andalucía, Camino Tiro Pichón s/n, 11500 El Puerto de Santa María, Cádiz, Spain

4Universidad de Málaga, Departamento de Microbiologia, Campus de Teatinos, 29071, Málaga, Spain

5Fitoplanton Marino S.L., 11500, El Puerto de Santa María, Spain

6“Crecimiento Azul", Centro IFAPA El Toruño, Unidad Asociada al CSIC”



The hatchery phase of aquaculture species is crucial for subsequent performance at the grow-out stage. It is during the hatchery stage that the organs and tissue essential for survival and the transition to the juvenile stage are laid down. Hatchery production of flatfish have specific challenges associated with the transition from a bilaterally symmetric larvae to an asymmetric juvenile, a process known as metamorphosis. The transition from larva to juveniles is associated with a shift in ecology and as well as the overt change in phenotype there is maturation of physiological systems. The risks of disease in aquaculture production has raised interest in the timing and ontogeny of immune competence and the way in which disease resistance can be reinforced in larval stages with positive impacts on grow-out stages. Vaccination is one successful strategy for disease control but requires that immunological memory exists and can only be used when competence of acquired immunity exists. Alternative strategies to strengthen and prime the immune system is the use of pre- and probiotics to enhance the immune competence. The present talk will present the ontogeny of the immune system in the sole relative to other species and consider how prebiotic stimulation affects immune system maturation and the larval microbiome.



This research has been funded by H2020 European Funds MSCA-RISE project 691102 (Algae4A&B) and the institutional project CCMAR/Multi/04326/2013 from the Portuguese Foundation for Science and Technology (FCT). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the abstract.